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Fetuin A Association in Periodontal Disease and Diabetes Mellitus

NCT06064786 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 45

Last updated 2023-10-03

No results posted yet for this study

Summary

Aim: The aim of the current study was to compare and correlate gingival crevicular fluid (GCF) fetuin-A levels and high sensitivity C-reactive protein (hs-CRP) levels in non-diabetic periodontitis patients and type 2 diabetic periodontitis patients with healthy subjects and revealing its possible role in diagnosis of periodontal disease.

Methodology: Forty-five periodontitis stage III patients categorized into 3 groups according to whether having type II diabetes mellitus or not were compared to systemically and periodontally healthy participants in this investigation. Clinical parameters for all groups were recorded. Assessment of GCF levels of fetuin A and hs-CRP were done to all enrolled participants utilizing an enzyme linked immune-sorbent assay (ELISA) kit. Receiver operating characteristic (ROC) curve was performed to reveal sensitivity, specificity, predictive value and diagnostic accuracy of the markers used.

Conditions

  • Periodontitis, Adult

Interventions

DIAGNOSTIC_TEST

GCF levels of fetuin A and hsCRP evaluation

ELIZA kits are used for GCF levels of fetuin A and hsCRP evaluation

Sponsors & Collaborators

  • Fayoum University

    lead OTHER

Eligibility

Min Age
20 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-08-01
Primary Completion
2023-09-15
Completion
2023-09-15

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06064786 on ClinicalTrials.gov