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Examining the Circadian Timing Effects of the Hypotensive Response to Exercise

NCT07049783 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2025-08-17

No results posted yet for this study

Summary

The goal of this study is to learn how exercise timing affects blood pressure in adults with elevated or high blood pressure. Exercise can influence the body's natural 24-hour rhythms, including blood pressure patterns. A single exercise session can lower blood pressure for up to 24 hours, but it is not fully understood how the time-of-day for exercise affects this response. The main question this study aims to answer is:

• When the same participant exercises at different times of day (morning, afternoon, or evening), how does this affect the participant's blood pressure over the next 24 hours?

Participants will:

* Undergo an in-lab assessment of individual biological rhythm that will indicate the clock-time for an individual's biological night
* Complete 3 supervised treadmill exercise sessions

* 1 in the biological morning (biological night + 10 hours)
* 1 in the biological afternoon (biological night + 15 hours)
* 1 in the biological evening (biological night + 20 hours)
* Complete a 24-hour blood pressure assessment before and after each exercise session

Conditions

  • Young Adults
  • Hypertension
  • Post-Exercise Hypotension
  • Circadian Rhythm

Interventions

BEHAVIORAL

Exercise

A single standardized, in-lab, 30-minute monitored treadmill exercise session

Sponsors & Collaborators

  • Freda Patterson

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
39 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-07-22
Primary Completion
2026-09-30
Completion
2026-09-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07049783 on ClinicalTrials.gov