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Monitoring of Breathing Effort Through Pressure Time Product Measurement Using Airway Occlusion Pressure

NCT06040138 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2024-03-12

No results posted yet for this study

Summary

Mechanical ventilation is essential in the management of patients in Intensive Care. The approach to patients with prolonged weaning is challenging.In this context, it is vital to implement "diaphragmatic protection" strategies, which consist of programming the level of ventilator assistance focused on sustaining the muscular effort within an objective range. The reference method for measuring inspiratory effort is the Pressure-Time Product (PTP) of the esophagus.

Recently, Bertoni et al. proposed the measurement of Occlusion Pressure as a non-invasive method, without the need to assess esophageal pressure, to estimate the magnitude of the effort and program assistance. Although it is a validated measurement for quantifying effort, it does not consider the duration of the effort performed by the patient, as well as the respiratory rate, two fundamental variables in terms of tolerance to the load. Therefore, the investigators propose the following study that will seek to validate the measurement of PTP in from the Occlusion Pressure, but considering inspiratory time and respiratory rate to obtain PTP per breath and per minute.

Conditions

Interventions

DIAGNOSTIC_TEST

End expiratory occlusion maneuver

An end expiratory occlusion maneuver will be performed during pressure support ventilation in patients with prolonged weaning.

Sponsors & Collaborators

  • HOSPITAL BRITANICO DE BUENOS AIRES

    collaborator OTHER

  • Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno

    collaborator OTHER

  • Sanatorio Anchorena San Martin

    collaborator OTHER

  • Hospital Italiano de Buenos Aires

    lead OTHER

Principal Investigators

  • Emilio Steinberg, RT · Hospital Italiano

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-10-01
Primary Completion
2024-07-01
Completion
2024-07-01

Countries

  • Argentina

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06040138 on ClinicalTrials.gov