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Effect of Increased Muscular Work During Different Weaning Strategies in Critically Ill Patients

NCT00538746 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2007-10-03

No results posted yet for this study

Summary

Most patients admitted to intensive care units require mechanical ventilation. Weaning from assisted/controlled ventilation begins when we recognize that the patient has recovered adeguately from acute respiratory failure.

If weaning is delayed, costs are increased, as are the risks of nosocomial pneumonia, cardiac-associated morbility, and death. On the other hand, weaning too soon often results in reintubation, which is associated with complications similar to those of prolonged ventilation.

The aim of this trial is to establish an evidence-based approach to weaning and to determine when a patient is ready to be weaned from mechanical ventilation, and what is the best weaning technique.

Conditions

  • Acute Respiratory Failure

Interventions

DEVICE

BIPAP

DEVICE

PSV

DEVICE

PSV + CPAP

Sponsors & Collaborators

  • Università degli Studi dell'Insubria

    lead OTHER

Principal Investigators

  • Paolo Pelosi, Professor · Universita' degli Studi dell'Insubria

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-02-28

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00538746 on ClinicalTrials.gov