MedTrace Logo

Comparison of Two Ventilator Mode During the Night: New Strategy of Mechanical Ventilation Weaning

NCT01573481 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 19

Last updated 2025-09-19

No results posted yet for this study

Summary

The purpose of the study is to compare pressure controlled continuous mandatory ventilation versus pressure support ventilation during the night for weaning to mechanical ventilation in chronic obstructive pulmonary disease patients and their impact onto sleep quality.

Conditions

  • Weaning Failure
  • COPD Exacerbation

Interventions

OTHER

pressure support ventilation

Patients in this group are ventilated during the night with pressure support ventilation mode. The level of the pressure support is the same as the previous day.

OTHER

Pressure controlled ventilation

Patients in this group are ventilated during the night (10 PM to 9 AM) with pressure controlled ventilation mode. The level of inspiratory pressure is set to 20 cm H2O and the respiratory rate is adjusted to avoid any spontaneous breathing (respiratory rate \> or equal to 12 breath per min).

Sponsors & Collaborators

  • Centre Hospitalier Universitaire, Amiens

    lead OTHER

Principal Investigators

  • ANDREJAK Claire, MD · CHU Amiens

  • JOUNIEAUX Vincent, MD PhD · CHU Amiens

  • BASILLE Damien, MD · CHU Amiens

  • ROGER Pierre-Alexandre, MD · CHU Amiens

  • ROSE Dominique, MD · CHU Amiens

  • MONCONDUIT Julien, MD · CHU Amiens

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-01-31
Primary Completion
2015-01-31
Completion
2015-01-31

Countries

  • France

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01573481 on ClinicalTrials.gov