Evaluation of Speech Rhythm Training in Dyslexic Readers Aged 7 to 9 Years

NCT05996497 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 160

Last updated 2025-03-03

No results posted yet for this study

Summary

Studies of dyslexia have shown altered oscillatory activity in the low gamma band (\~25-35 Hz) in the left auditory cortex. Neural oscillations around 30 Hz constitute the basic sampling rate of speech, from which the ability to form specific phonemic categories on which reading learning is based is derived. An alteration of the oscillatory activity at 30 Hz could therefore influence the ability of children to learn to read, and explain the reading deficit observed in children with a specific written language disorder. The objective of our study is to determine whether intensive rhythmic auditory stimulation applied during 30 sessions of 15 minutes spread over 6 weeks (5 sessions per week) can correct neural oscillations in the gamma-low band, allowing an improvement of phonemic categorization abilities, and thus the reading abilities of dyslexic readers aged 7 to 9 years. The long-term objective of this study is to test the therapeutic potential of auditory stimulation with speech rhythms for the treatment of reading disorders.

Conditions

  • Dyslexia

Interventions

BEHAVIORAL

behavioral measures

behavioral measures

OTHER

Electrophysiological measures

Electrophysiological measures

OTHER

Training 1

Training 1

OTHER

Training 2

Training 2

Sponsors & Collaborators

  • Institut de l'Audition

    collaborator OTHER
  • Institut Pasteur

    lead INDUSTRY

Principal Investigators

  • Diane Lazard, MD · Institut Pasteur

  • Anne-Lise Giraud, PhD · Institut Pasteur

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
7 Years
Max Age
9 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-10-05
Primary Completion
2026-01-01
Completion
2026-07-01

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05996497 on ClinicalTrials.gov