MedTrace Logo

Biological Aging of Skeletal Muscles in Humans

NCT02675192 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 72

Last updated 2021-11-17

No results posted yet for this study

Summary

Aging affects almost all the tissues and physiological functions, and skeletal muscle is the most affected organ. The progressive decline of the weight and the muscular function linked to the aging contributes to the lack of autonomy and dependence, but also to an increase of the mortality risks. Sarcopenia is also a prevalent condition, because it is detected in 13-24% of 60 years old, and 50% of 80 years old and more.

However, strong inter-individual variations of this prevalence of sarcopenia exists. The key issue is to understand why the biological aging of the skeletal muscle is so different between people.

In this study, mechanisms involved in biological aging of the skeletal muscle in aging people (same chronological age) will be specified.

Conditions

  • HEALTHY

Interventions

OTHER

Proof cohort : muscular assessment

Clinical examination, blood appraisal, urinary collection, MVC, checking muscle functional skills and muscular biopsy will be performed.

Sponsors & Collaborators

  • Ecole Nationale Superieure Lyon

    collaborator UNKNOWN

  • Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

    collaborator OTHER

  • Region Rhone Alpes

    collaborator UNKNOWN

  • Centre Hospitalier Universitaire de Saint Etienne

    lead OTHER

Principal Investigators

  • FEASSON Léonard, MD · CHU SAINT-ETIENNE

Eligibility

Min Age
80 Years
Max Age
83 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-02-18
Primary Completion
2017-01-20
Completion
2017-05-23

Countries

  • France

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02675192 on ClinicalTrials.gov