Diuretic Efficacy of Aminophylline and Furosemide Combination vs Furosemide Alone in Critically Ill Adults
NCT05933642 · Status: UNKNOWN · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 132
Last updated 2023-07-11
Summary
The goal of this RCT is to compare the effectiveness of aminophylline and furosemide combination vs furosemide alone in producing effective diuresis in critically ill adults in ICU. ICU patients with the need of improved diuresis will be recruited and given either infusion of aminophylline and furosemide combination or furosemide alone, and their hourly urine output will be monitored to compare their effectiveness.
Conditions
Interventions
- DRUG
-
Aminophylline
aminophylline 150mg
- DRUG
-
Frusemide
frusemide 120mg
Sponsors & Collaborators
-
University of Malaya
lead OTHER
Principal Investigators
-
Haw Shyan Ng · University of Malaya
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-07-02
- Primary Completion
- 2023-12-31
- Completion
- 2023-12-31
Countries
- Malaysia
Study Locations
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