Furosemide Stress Test to Predict Successful Liberation From RRT

NCT05612490 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 52

Last updated 2025-08-12

No results posted yet for this study

Summary

The proposed study will evaluate if a standardised dose of furosemide administered in the 12 hours after RRT liberation can predict successful liberation in critically ill patients. The dose that will be administered is in accordance with the prescribing information.

Conditions

Interventions

DRUG

Furosemide stress test

The FST corresponds to the intravenous single-dose administration of 1 mg/kg (1.5 mg/kg in previously exposed patients) of furosemide and the assessment of resulting diuresis in the following two hours. In the 12 hours following the first RRT liberation, a FST will be performed. The test will be considered positive if urinary output is ≥200 mL in the two hours following furosemide administration.

Sponsors & Collaborators

  • Centre Hospitalier Universitaire Vaudois

    lead OTHER

Principal Investigators

  • Antoine Schneider, MD PhD · Centre Hospitalier Universitaire Vaudois

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-01-17
Primary Completion
2025-06-04
Completion
2025-07-09
FDA Drug
Yes

Countries

  • Switzerland

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05612490 on ClinicalTrials.gov