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Assessment of the Effect of Non-surgical Periodontal Treatment on Endothelial Function- a Prospective Study

NCT05691426 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2023-01-25

No results posted yet for this study

Summary

An association between periodontitis and endothelial dysfunction has been reported, suggesting that periodontitis presents an inflammatory burden to the cardiovascular system, that might lead to AVD. The study aims aim to assess whether non-surgical periodontal therapy enhances endothelial function in periodontitis patients using a non-invasive diagnostic device to assess endothelial function through PWA and the assessment of levels of salivary Endothelin-1, in a population of people in the UAE.

Conditions

  • Endothelial Dysfunction
  • Periodontal Diseases

Interventions

DIAGNOSTIC_TEST

Assessment of pulse wave amplitude (PWA)

Assessment of pulse wave amplitude (PWA) through peripheral arterial tonometry (PAT) using the device EndoPAT (Itamar Medical)

DIAGNOSTIC_TEST

Salivary Nitric Oxide

assessment the levels of salivary Nitric Oxide using a Nitric Oxide colorimetric detection kit,

Sponsors & Collaborators

  • University of Sharjah

    lead OTHER

Principal Investigators

  • Zahi Badran · University of Sharjah

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-10-01
Primary Completion
2023-12-31
Completion
2024-06-30

Countries

  • United Arab Emirates

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05691426 on ClinicalTrials.gov