HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets
NCT05873634 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000
Last updated 2026-04-13
Summary
HeartShare is a comprehensive study of heart failure, a common and serious medical condition which occurs when the heart is unable to keep up with the demands of the body, resulting in shortness of breath, fluid retention, and fatigue. HeartShare aims to better classify heart failure into subtypes to help develop more personalized treatments for patients, with the hope that this will improve the lives of heart failure patients. To do this, HeartShare is bringing together a large amount of data (including images, such as heart ultrasounds and MRIs and molecular data from the blood, such as genetics) from previously conducted studies and electronic health records, and is gathering new data through participants enrolled in the HeartShare Deep Phenotyping Study.
Conditions
Sponsors & Collaborators
-
National Heart, Lung, and Blood Institute (NHLBI)
collaborator NIH -
Massachusetts General Hospital
collaborator OTHER -
Brigham and Women's Hospital
collaborator OTHER - collaborator OTHER
-
University of California, Davis
collaborator OTHER -
Wake Forest University Health Sciences
collaborator OTHER - collaborator OTHER
- lead OTHER
Principal Investigators
-
Sanjiv Shah, MD · Northwestern University
-
Svati Shah, MD, MHS · Duke University
-
Javed Butler, MPH, MBA · Baylor Scott and White Health
Eligibility
- Min Age
- 30 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2023-03-01
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
Countries
- United States
Study Locations
More Related Trials
-
Value of Intense Phenotyping in Heart Failure With Preserved Ejection Fraction
NCT05479669 ·Status: RECRUITING
-
Assessment of Biomarkers in Patients With Decompensated Heart Failure and Underlying Coronary Artery Disease
NCT03551756 ·Status: UNKNOWN
-
How the Elderly Live With Pain in Heart Failure
NCT01794728 ·Status: COMPLETED
-
ESCAPE Mechanistic Substudies - Ancillary to ESCAPE
NCT00021957 ·Status: COMPLETED
-
Cardiometabolic evalUation REgistry of Heart Failure
NCT06939985 ·Status: RECRUITING
-
Multiparametric Assessment of Cardiac Congestion in Outpatient Worsening Heart Failure
NCT05747820 ·Status: COMPLETED
-
ConnectedHeartHealth - Heart Failure Readmission Intervention
NCT03247608 ·Status: COMPLETED ·Phase: NA
-
Implementing a Digitally-enabled Community Health Worker Intervention for Patients With Heart Failure
NCT05130008 ·Status: COMPLETED ·Phase: NA
-
Multi-Center Project: Building Electronic Tools To Enhance and Reinforce CArdiovascular REcommendations - Heart Failure
NCT06457152 ·Status: COMPLETED ·Phase: NA
-
Monitoring Community Trends in Heart Failure
NCT00035724 ·Status: COMPLETED
-
The SWISSHEART Failure Network (SHFN)
NCT05603247 ·Status: UNKNOWN
-
Characteristics, Phenotypes, and TRAITS of Heart Failure With Preserved Ejection Fraction (TRAITS-HFpEF)
NCT05383287 ·Status: RECRUITING
-
Heart Failure and a Preserved Ejection Fraction
NCT00586833 ·Status: COMPLETED
-
DIGITAL-HF - Digital Tools in Heart Failure - a Survey of Patient Usage (DIGITAL-HF)
NCT05313880 ·Status: COMPLETED
-
Community Surveillance of Congestive Heart Failure
NCT00005517 ·Status: COMPLETED
-
Congestive Heart Failure Pilot Study Utilizing Wireless Home Scale and Daily Symptom Monitoring
NCT03234088 ·Status: COMPLETED ·Phase: NA
-
Assessment of The Clinical Course of Dyspnea in Acute Heart Failure Patients
NCT01615926 ·Status: TERMINATED
-
Comparison of Outcomes and Access to Care for Heart Failure Trial
NCT02674438 ·Status: COMPLETED ·Phase: PHASE3
-
Pilot and Feasibility Study of a MAWDS (Medications, Activity, Weight, Diet and Symptoms) Heart Failure Mobile Platform
NCT03294512 ·Status: COMPLETED ·Phase: NA
-
The Optimization of Medications in Chronic Heart Failure Using a Website
NCT04580004 ·Status: TERMINATED ·Phase: NA
-
Future Innovations in Novel Detection of Heart Failure FIND-HF
NCT05756127 ·Status: ACTIVE_NOT_RECRUITING
-
Care Coordination to Assess Improvement in Outcomes in Hospital Readmissions
NCT04905160 ·Status: RECRUITING ·Phase: NA
-
Improving Care of Patients With Heart Failure
NCT01461681 ·Status: COMPLETED ·Phase: NA
-
Utilising AI Analysis of Sounds To prEdict heaRt failurE decOmpensation
NCT06555757 ·Status: RECRUITING
-
SCREEN-HFL (SCReening Evaluation of the Evolution of New Heart Failure) - a Longitudinal Study
NCT01581827 ·Status: COMPLETED