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Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction

NCT06517186 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 180

Last updated 2026-04-09

No results posted yet for this study

Summary

The purpose of this study is to identify changes in heart tissue structure and biological function in patients with heart failure by performing an endomyocardial biopsy (EMB or heart biopsy) during a right heart catheterization (RHC). The ultimate goal is to use this information to develop new treatments for heart failure.

Conditions

Sponsors & Collaborators

  • National Heart, Lung, and Blood Institute (NHLBI)

    collaborator NIH

  • Massachusetts General Hospital

    collaborator OTHER

  • Brigham and Women's Hospital

    collaborator OTHER

  • Mayo Clinic

    collaborator OTHER

  • Wake Forest University Health Sciences

    collaborator OTHER

  • University of Pennsylvania

    collaborator OTHER

  • Northwestern University

    lead OTHER

Principal Investigators

  • Sanjiv Shah, MD · Northwestern University

  • Margaret Redfield, MD · Mayo Clinic

Eligibility

Min Age
30 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-11-08
Primary Completion
2026-12-31
Completion
2026-12-31

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06517186 on ClinicalTrials.gov