Immuno-Positron Emission Tomography (PET)-Glioma Study, a Proof-of-principle Imaging Study
NCT05753995 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2025-04-01
Summary
Imaging of proinflammatory activated microglia by Purine 2X7 (P2X7) receptor scintigraphy in Positron Emission Tomography (PET) scanner in Glioblastoma patients.
Conditions
Interventions
- DIAGNOSTIC_TEST
-
PET imaging
The evaluation of PET imaging using PET ligand \[18F\]JNJ-64413739 or a \[18F\] labeled equivalent in vivo in patients.
Sponsors & Collaborators
-
Kepler University Hospital
lead OTHER
Principal Investigators
-
Robert Pichler, PD, MD · Kepler University Hospital
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-03-01
- Primary Completion
- 2025-12-01
- Completion
- 2026-12-01
Countries
- Austria
Study Locations
More Related Trials
-
TSPO-PET/MRI in Surveillance of Neuroinflammation in the Central Nervous System
NCT06467773 ·Status: RECRUITING
-
The GBA Multimodal Study in Parkinson's Disease
NCT04101968 ·Status: RECRUITING
-
A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions
NCT00870974 ·Status: COMPLETED ·Phase: PHASE1
-
Targeted Translocator Protein PET Imaging Evaluate Neuroinflammation of the Chronic Pain Patients
NCT06701734 ·Status: NOT_YET_RECRUITING
-
(68^Ga)-GaPSMA-11 PET/MR-imaging of Malignant Intra-axial Brain Tumors
NCT05798273 ·Status: COMPLETED ·Phase: NA
-
Gadolinium and Ferumoxytol MRI in Diagnosing Patients With Abnormalities in the Central Nervous System
NCT03270059 ·Status: RECRUITING ·Phase: PHASE2
-
18F-DPA-714 PET/MR in Dysfunctional Brain Diseases
NCT06851143 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
MRI Detection of Microbleeds in Glioma Patients
NCT02899663 ·Status: COMPLETED
-
A Study of Imaging in Demyelinating Diseases
NCT05805839 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE2
-
Developing a Novel Imaging Biomarker in the Differential Diagnosis of Parkinson's Disease and Parkinsonism
NCT02059733 ·Status: COMPLETED ·Phase: PHASE2
-
Impact of Confirmed Autoimmune Encephalitis on Brain Glucose Metabolism
NCT06079294 ·Status: RECRUITING ·Phase: NA
-
Brain Imaging and Retreatment Study of Persistent Lyme Disease
NCT00037479 ·Status: COMPLETED ·Phase: PHASE2
-
Magnetic Resonance Imaging in Immune Effector Cell-Associated Neurotoxicity Syndrome
NCT05510596 ·Status: COMPLETED ·Phase: NA
-
Microglial Cells Activation Imaging Using PET-CT With 18F-DPA714
NCT04171882 ·Status: UNKNOWN
-
Magnetic Resonance Imaging Evaluation of the Tissular Oxygen Saturation in Brain
NCT02317055 ·Status: TERMINATED ·Phase: NA
-
PET Brain Imaging in Multiple Sclerosis, Alzheimer's Disease, and Other Neurological and Neuropsychiatric Diseases
NCT02649985 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Development of MRI Protocols and Associated Neuro-physiological Explorations in Healthy and Pathological Subjects
NCT05036629 ·Status: RECRUITING ·Phase: NA
-
Cerebral Metabolic Changes Associated With Thalamic Stimulation
NCT01141764 ·Status: TERMINATED ·Phase: PHASE3
-
PET-imaging of Unruptured Intracranial Aneurysm Inflammation
NCT04715503 ·Status: UNKNOWN ·Phase: NA
-
Excitatory Amino Acids and Activated Microglia After Traumatic Brain Injury: a (R)-[11C]PK11195 PET Study
NCT00205582 ·Status: UNKNOWN ·Phase: PHASE1
-
PET Imaging of Neuroinflammation in Neurodegenerative Diseases Via a Novel Translocator Protein (TSPO) Radioligand
NCT03958630 ·Status: TERMINATED ·Phase: PHASE1
-
Metabolic Imaging of Neurological Disease
NCT06900244 ·Status: ENROLLING_BY_INVITATION
-
Single Photon Emission Computed Tomography/Computed Tomography With Pentavalent 99mTc Dimercaptosuccinic Acid in Patients With Brain Glioma; Correlation With IDH Mutation
NCT05593809 ·Status: UNKNOWN
-
PET-MRI Imaging in Patients With Acute Neurovascular Syndrome
NCT03215563 ·Status: COMPLETED
-
Molecular Imaging of NET Using [C-11]MRB-PET in MS
NCT03207464 ·Status: RECRUITING ·Phase: PHASE1/PHASE2