18F-DPA-714 PET/MR in Dysfunctional Brain Diseases
NCT06851143 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 65
Last updated 2025-02-28
Summary
This is a diagnostic pilot study that recruited 25 normal volunteers and 40 patients with dysfunctional brain diseases and performed 18F-DPA-714 PET/MR imaging to evaluate the correlation between the multimodal imaging features of dysfunctional brain diseases, to explore the potential pathological mechanisms of neuroimmune activation, and to further analyse the value of PET/MR-based multimodal imaging in the diagnosis and differential diagnosis of dysfunctional brain diseases. and further analyse the diagnostic and differential diagnostic value of PET/MR-based multimodal imaging in dysfunctional brain diseases.
Conditions
- Brain Disease
Interventions
- DIAGNOSTIC_TEST
-
18F-DPA-714 PET/MR scan
Saline intravenous solution of 18F-DPA-714 administered at 0.1 mCi/kg by bodyweight
Sponsors & Collaborators
-
Xijing Hospital
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-03-01
- Primary Completion
- 2027-12-31
- Completion
- 2027-12-31
More Related Trials
-
Microglial Cells Activation Imaging Using PET-CT With 18F-DPA714
NCT04171882 ·Status: UNKNOWN
-
Developing a Novel Imaging Biomarker in the Differential Diagnosis of Parkinson's Disease and Parkinsonism
NCT02059733 ·Status: COMPLETED ·Phase: PHASE2
-
Clinical Applicantion of Multi-Tracer PET/MR Imaging in Neurological Disorders/Disease
NCT06092125 ·Status: RECRUITING
-
Neuroinflammatory PET Imaging in Autoimmune Encephalomyelitis
NCT05293405 ·Status: UNKNOWN ·Phase: NA
-
Study on Data Acquisition and Image Characteristics of Brain Multifrequency EIT in Healthy People and Patients With Brain Diseases
NCT05796349 ·Status: COMPLETED
-
A Study of Imaging in Demyelinating Diseases
NCT05805839 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE2
-
PET with [18F]Flumazenil As an Index of Neurodegeneration in MS
NCT03825601 ·Status: COMPLETED ·Phase: NA
-
Aβ PET and Tau PET Imaging in the Diagnosis and Progression Assessment of Alzheimer's Disease
NCT07114224 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Targeted Translocator Protein PET Imaging Evaluate Neuroinflammation of the Chronic Pain Patients
NCT06701734 ·Status: NOT_YET_RECRUITING
-
Structural and Functional Impairment of Multiple Organs in Patients With Systemic Sclerosis: A MR Imaging Study
NCT05297474 ·Status: UNKNOWN
-
A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions
NCT00870974 ·Status: COMPLETED ·Phase: PHASE1
-
An fMRI Study of Jianpi Yishen Huatan Granules for Cognitive Impairment After Acute Cerebral Infarction
NCT02752867 ·Status: UNKNOWN ·Phase: NA
-
Beta Amyloid PET/CT in Various Aβ-Related Disease
NCT06725706 ·Status: RECRUITING
-
Multimodal MR Imaging in Patients With Glioblastoma Treated With Dendritic Cell Therapy
NCT01657734 ·Status: COMPLETED
-
Analysis of Brain Diffusion Tensor Image in Stroke Patients
NCT06047223 ·Status: RECRUITING
-
Optimization and Harmonization of Advanced MRI Sequences
NCT06217237 ·Status: COMPLETED
-
PET Imaging of the Translocator Proteine Ligands (TSPO) With [18 F] DPA-714 Biomarker of NeuroInflammation in Cognitive Decline (NIDECO)
NCT02062099 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluation of the Neuroinflammation Pattern of BAY85-8102 F-18, DPA-714 in Probable Alzheimers Disease Patients Versus Healthy Volunteers and Radiation Dosimetry of F 18, DPA-714 in Healthy Volunteers
NCT01009359 ·Status: COMPLETED ·Phase: PHASE1
-
Synaptic Density, Tau and Multiparametric PET-MR in Brain Trauma, Stroke and Mild Cognitive or Behavioral Impairment.
NCT03514524 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Magnetic Resonance Imaging for the Study of Patients With Neurological Disorders
NCT00001362 ·Status: COMPLETED
-
MECHANISMS OF NEURONAL RESILIENCE IN ALZHEIMER'S DISEASE AND ITS FOCAL VARIANTS: A PET/MR STUDY
NCT04150198 ·Status: RECRUITING ·Phase: NA
-
Creation of a Probabilistic Atlas of Normal Cerebral Uptake of 18F-FDG in PET/MRI.
NCT05355857 ·Status: COMPLETED ·Phase: NA
-
CSF1R PET Probe [18F]CSF-23 in Alzheimer's Disease Brain Imaging
NCT06148233 ·Status: RECRUITING ·Phase: NA
-
Prognosis Value of the Neuronal Damage in Early Multiple Sclerosis
NCT01651520 ·Status: UNKNOWN ·Phase: NA
-
Discard the Curative Causes of Late Onset Epilepsy: the Role of Brain 18F-FDG PET
NCT05831371 ·Status: UNKNOWN