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MR Evidence of Cardiac Inflammation Post-Stroke

NCT05714618 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 44

Last updated 2024-09-20

No results posted yet for this study

Summary

The present study is an investigator initiated, single-centre, prospective, proof-of-concept cohort study aiming to enroll 44 patients with acute middle cerebral artery (MCA) ischemic stroke, involving the right (n=22) and left (n=22) MCA territories and 24 control patients with acute focal neurological symptoms but no evidence of acute brain infarct on DWI-MRI.

Conditions

Interventions

DIAGNOSTIC_TEST

Gadolinium-enhanced cardiac MRI

Cardiac magnetic resonance imaging (MRI) with a protocol designed to measure myocardial inflammation and fibrosis.

DIAGNOSTIC_TEST

B Natriuretic Peptide

Measurement of B Natriuretic Peptide on patients' blood samples at 10 and 60+/-15 days.

DIAGNOSTIC_TEST

Systemic inflammatory markers

Measurement of a panel of 92 systemic inflammatory markers on patients' blood samples at 10 and 60+/-15 days.

Sponsors & Collaborators

  • McMaster University

    collaborator OTHER

  • Western University, Canada

    collaborator OTHER

  • London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

    lead OTHER

Principal Investigators

  • Luciano Sposato, MD · London Health Sciences Center, Western University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-10-01
Primary Completion
2025-06-16
Completion
2025-12-31

Countries

  • Canada

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05714618 on ClinicalTrials.gov