Neuroinflammation After Myocardial Infarction - Imaging Substudy
NCT03968445 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 6
Last updated 2025-12-11
Summary
The purpose of the study is to see if positron emission tomography and magnetic resonance imaging (PET/MRI) with an investigational drug called \[18F\]DPA-714 will show inflammation in the brain after a heart attack. This study may help physicians and researchers better understand the role of brain inflammation in heart disease and develop new treatments to protect the brain.
Conditions
Interventions
- DRUG
-
[18F]DPA-714-PET/MRI
\[18F\]DPA-714-PET/MRI
Sponsors & Collaborators
-
University of Alabama at Birmingham
lead OTHER
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 21 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-10-17
- Primary Completion
- 2028-10-31
- Completion
- 2028-10-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Understanding the Metabolic and Functional Derangement of Primary Mitral Regurgitation: a Feasibility Study Using Carbon 11(C-11) Acetate Cardiac Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI)
NCT04795856 ·Status: WITHDRAWN ·Phase: EARLY_PHASE1
-
18F-fluorocholine PET-MR Imaging of Coronary Plaque Vulnerability
NCT03252990 ·Status: COMPLETED
-
PET MRI in Coronary Artery Disease
NCT03451448 ·Status: COMPLETED
-
Magnetic Resonance Imaging (MRI) Viability: Comparison of Myocardial Viability by Positron Emission Tomography and MRI
NCT00166179 ·Status: COMPLETED
-
MRI of Myocardial Infarction
NCT03531151 ·Status: COMPLETED
-
Technical Development of Cardiovascular Magnetic Resonance Imaging
NCT00027170 ·Status: COMPLETED
-
Myocardial Perfusion Imaging by Combined 15O-H2O PET and MR
NCT04940247 ·Status: COMPLETED
-
Comprehensive Evaluation of Ischemic Heart Disease Using MRI
NCT01234870 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Using Cardiac MRI to Predict Outcomes in Patients With STEMI
NCT07072858 ·Status: RECRUITING
-
Evaluate the Effectiveness and Cost of Stress Cardiac Magnetic Resonance Imaging (MRI) for Non-invasive Evaluation of Lesions Discovered on Computed Tomography Angiography (CCTA)
NCT00538460 ·Status: TERMINATED
-
PET/CT Study in the Diagnosis of Coronary Plaque
NCT00850473 ·Status: TERMINATED ·Phase: NA
-
Residual Inflammation and Plaque Progression Long-term Evaluation
NCT04073810 ·Status: ACTIVE_NOT_RECRUITING
-
Magnetic Resonance Imaging to Detect Blood Vessel Inflammation in Patients Undergoing Peripheral Balloon Angioplasty
NCT00004549 ·Status: COMPLETED ·Phase: PHASE1
-
Magnetic Resonance Angiography to Diagnose Atherosclerotic Disease
NCT00382564 ·Status: COMPLETED
-
Myocardial Salvage Assessed by Cardiovascular Magnetic Resonance - Impact on Outcome
NCT00952224 ·Status: COMPLETED
-
Efficacy of Non Contrast DWI(Diffusion Weighted Imaging) Imaging Compared to DMR-DE
NCT01820000 ·Status: COMPLETED ·Phase: NA
-
Cardiac Fibroblast Activation Detected by 68Ga-FAPI PET/MR
NCT04723953 ·Status: COMPLETED ·Phase: NA
-
Cardiac MRI in Myocarditis and Inflammatory Cardiomyopathy
NCT07325968 ·Status: ENROLLING_BY_INVITATION
-
In-vivo Thrombus Imaging With 18F-GP1, a Novel Platelet PET Radiotracer
NCT03943966 ·Status: COMPLETED ·Phase: NA
-
Impact of Coronary Artery Stenting on Quantitative Myocardial Blood Flow and Health Status
NCT04475094 ·Status: UNKNOWN
-
Coronary Atherosclerosis Evaluation by Arterial Wall Magnetic Resonance Imaging (MRI)
NCT00353795 ·Status: COMPLETED ·Phase: NA
-
Prognostic Role of LA Strain in Acute Myocardial Infarction
NCT06408636 ·Status: COMPLETED
-
Study of Novel PET Tracer Gallium [68Ga]/ Fluorine [18F] -FAPI-04 in the Diagnosis of Cardiovascular Diseases
NCT05867589 ·Status: RECRUITING ·Phase: NA
-
Clinical Study of CMR to Evaluate the Effect of Ivabradine on the Improvement of Left Ventricular Remodeling in STEMI Patients After Primary PCI
NCT05348057 ·Status: UNKNOWN ·Phase: PHASE4
-
Intracoronary Thrombus Detection by Magnetic Resonance Imaging
NCT02776657 ·Status: COMPLETED ·Phase: NA