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INflammation and Small Vessel Disease Study

NCT05746221 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2023-02-27

No results posted yet for this study

Summary

A prospective observational cohort study in patients with cerebral small vessel disease deterring whether changes in systemic inflammation predict brain white matter damage measured using MRI and cognitive decline. This is a study funded by a joint BHF-Dutch Heart Foundation research grant and will be conducted in both Cambridge UK and Nijmegen Netherlands with 100 of the 200 total participants recruited at each site, and data from both sites analysed together.

Conditions

Sponsors & Collaborators

  • Radboud University Medical Center

    collaborator OTHER

  • Wolfson Brain Imaging Centre

    collaborator UNKNOWN

  • University of Cambridge

    lead OTHER

Principal Investigators

  • Hugh S Markus · University of Cambridge

Eligibility

Min Age
40 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-08-10
Primary Completion
2026-07-31
Completion
2026-07-31

Countries

  • Netherlands
  • United Kingdom

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05746221 on ClinicalTrials.gov