MedTrace Logo

Platelet-Directed Whole Blood Transfusion Strategy for Malaria

NCT05711485 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 132

Last updated 2025-10-09

No results posted yet for this study

Summary

Open-label randomized controlled trial to test the effectiveness of whole blood transfusion for improving survival in children with severe malaria complicated by thrombocytopenia.

Conditions

Interventions

OTHER

Whole blood transfusion

Whole blood is sourced from the Zambia National Blood Transfusion Service.

Sponsors & Collaborators

Principal Investigators

  • Matthew M Ippolito, MD, PhD · Johns Hopkins University

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
6 Months
Max Age
59 Months
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-02-24
Primary Completion
2027-04-30
Completion
2028-05-31

Countries

  • United States
  • Zambia

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05711485 on ClinicalTrials.gov