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The Effect of Paracetamol in the Treatment of Non-severe Malaria in Children in Guinea-Bissau

NCT00137566 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL

Last updated 2010-07-07

No results posted yet for this study

Summary

The National Malaria Programme in Guinea-Bissau recommends paracetamol for all children treated for malaria. We, the investigators of the Bandim Health Project, want to evaluate whether this treatment has any effect on:

* the well-being of the child;
* the parasite clearance time; and
* the rate of a re-appearance of parasites during 35 days of follow-up.

Children presenting at Bandim Health Centre with malaria will be treated with chloroquine plus paracetamol or chloroquine plus placebo. Blood samples will be obtained daily for the first 4 days and then once a week until day 35.

Conditions

Interventions

DRUG

acetaminophen (paracetamol)

Paracetamol tablets, 50 mg/kg/day for 3 days.

OTHER

Placebo

Sponsors & Collaborators

  • Bandim Health Project

    lead OTHER

Principal Investigators

  • Peter Aaby, Professor · Bandim Health Project

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Max Age
15 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-05-31
Primary Completion
2006-11-30
Completion
2010-01-31

Countries

  • Guinea-Bissau

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00137566 on ClinicalTrials.gov