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Impact of Periodontal Intervention on Vascular Dysfunction

NCT01917292 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 123

Last updated 2015-04-17

No results posted yet for this study

Summary

The purpose of this study is to determine the effect of periodontal intervention on vascular dysfunction among Chinese prehypertensive adults with moderate to severe periodontal disease.

Conditions

  • Chronic Periodontitis
  • Prehypertension

Interventions

PROCEDURE

One-Stage Full-Mouth Disinfection

1. Basic oral hygiene instructions 2. Dental extractions will be performed (only in cases of teeth that could not be saved) 3. Standard cycle of supragingival ultrasonic scaling and polishing 4. Scaling and root planning after the administration of local anesthesia, four quadrants in one session 5. Minocycline Hydrochloride Ointment (Periocline, OraPharma) were delivered locally into the periodontal pockets

PROCEDURE

Periodontal care

1. Basic oral hygiene instructions 2. Standard cycle of supragingival ultrasonic scaling and polishing

Sponsors & Collaborators

  • First Affiliated Hospital, Sun Yat-Sen University

    lead OTHER

Principal Investigators

  • Jun Ying Yang, Master · First Affiliated Hospital, Sun Yat-Sen University

  • Jun Tao, M.D.,phD. · First Affiliated Hospital, Sun Yat-Sen University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-12-31
Primary Completion
2013-12-31
Completion
2014-06-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01917292 on ClinicalTrials.gov