The Effect of Combination Mindfulness Spiritual-Based Cognitive Therapy Plus Hypnosis in HIV Patients With Depression

Summary

HIV/AIDS patients are at risk for depression, a multifactorial disorder with signs and symptoms that affect the cognitive, affective, behavioral, and somatic areas. This study used Randomized Controlled Clinical Trials (RCT).

Main hypothesis: A combination of spiritual awareness-based cognitive therapy (MSBCT) plus hypnotic interventions can reduce depression degree scores by reducing cortisol levels and increasing serotonin levels in HIV patients with depression.

Small hypothesis

1. There was a decrease in cortisol levels after being given the MSBCT plus hypnosis combination intervention in HIV patients with depression;
2. There was an increase in serotonin levels after being given the MSBCT plus hypnosis combination intervention in HIV patients with depression;
3. There was a decrease in depression degree scores after being given the MSBCT plus hypnosis combination intervention in HIV patients with depression;
4. There was a higher reduction in cortisol levels in the intervention group compared to the control group in HIV patients with depression;
5. There was a higher increase in serotonin levels in the intervention group compared to the control group in HIV patients with depression;
6. There was a higher reduction in scores degree of depression in the intervention group compared to the control group in HIV patients with depression;
7. Decreased cortisol levels and increased serotonin levels affect depression degree scores in HIV patients with depression;
8. MSBCT plus hypnosis combination intervention is a factor that can affect depression degree scores reduction in HIV patients with depression;

Conditions

• Depression

Interventions

BEHAVIORAL

Combination mindfulness spiritual-based cognitive therapy plus hypnosis

The intervention was divided into eight components in eight sessions, namely (1) psychoeducation and intention, (2) awareness of breathing mindfulness, (3) body scan, (4) comfort training through daily activity/comfort exercises, (5) self-compassion / having a great soul with acceptance, gratitude, and sincerity, (6) planning happiness through independent healthy behavior targets, (7) independent healthy behavior (8) independent healthy behavior evaluation. Each therapeutic component of each session is further divided into three sub-components, namely psychoeducation, training, and hypnosis.

BEHAVIORAL

Mindfulness-based cognitive therapy

The program curriculum consists of the automatic pilot; living in our heads; gathering the scattered mind; recognizing aversion; allowing and letting be; thoughts as thoughts; kindness in action; maintaining and extending new learning.

Sponsors & Collaborators

• Health Technology Institute of Cendekia Utama Kudus

  lead OTHER

Principal Investigators

• Eny Pujiati, M.Kes · Health Technology Institute of Cendekia Utama Kudus - Middle Java - Indonesia

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

60 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2020-12-12

Primary Completion

2021-04-10

Completion

2021-04-10

Countries

• Indonesia

Study Locations