MedTrace Logo

The Effectiveness of CBI on Depression and Adherence in HIV Infected Adolescents

NCT05482217 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25

Last updated 2022-08-01

No results posted yet for this study

Summary

Aim: To explore the effectiveness of psychoeducation and problem-solving (Life-steps) on depression and adherence in HIV-infected adolescents.

Methods: Forty-two adolescents were randomized into 21 controls and 21 intervention groups. The intervention group was exposed to 5-week sessions of life steps applied by a lay counselor. The PHQ-9 and visual analog scale (VAS) were used to measure the outcomes: depression and adherence. They were applied at baseline, 5-weeks, and 24 weeks post-intervention.

Conditions

  • Medication Nonadherence
  • Depression
  • HIV Infections

Interventions

BEHAVIORAL

Psychoeducation, problem solving and rehearsal (cognitive behavioural intervention)

The highlights of the intervention. Session 1: Rapport building and knowledge of HIV Session 2: Identifying and Dealing with barriers to good adherence Session 3: Identifying and dealing with problems in relation to depression and adherence: Session 4: Identifying and dealing with negative cognitions, handling privacy, accessing social Support, and adjusting to HIV and antiretroviral treatment Session 5: Rehearsal of practical tips on adherence, handling slips, and strategies to improve quality of life. All sessions involved brief periods of relaxation, homework, and a homework review. The last session was concluded with the assessment of satisfaction with the program. The programs were conducted for 60 minutes weekly for five weeks. They were delivered by a trained lay counselor and supervised by the principal investigator for five weeks.

Sponsors & Collaborators

  • University of KwaZulu

    collaborator OTHER

  • University of Botswana

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
12 Years
Max Age
19 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-07-26
Primary Completion
2021-11-02
Completion
2022-05-03

Countries

  • Botswana

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05482217 on ClinicalTrials.gov