Remote State Representation in Early Psychosis

Summary

The purpose of this study is to examine state representation in individuals aged 18-30 who have been diagnosed with a psychotic illness, as well as young adults who do not have a psychiatric diagnosis. State Representation is our ability to process information about our surroundings. The investigators will complete some observational tests as well as a cognitive training clinical trial.

Conditions

• Psychosis
• Schizophrenia
• Schizo Affective Disorder
• Schizoaffective Disorder
• Schizophreniform Disorders
• Psychotic Disorders
• Psychotic Mood Disorders
• Psychoses, Affective
• Psychosis Nos/Other
• Schizophrenia Spectrum and Other Psychotic Disorders

Interventions

DEVICE

BrainHQ Computerized Cognitive Training - Visual Perception Training Paradigm

The Cognitive Training is a program consisting of the follow set of exercises developed by Posit Science Corporation (BrainHQ) which is to be evaluated for Visual Perception Training: Visual Sweeps; Mind's Eye; Hawk Eye; and Divided Attention. Participants use a standard web browser on a broadband connected computer and go to the study web site. Participants perform multiple trials over the course of a session, with auditory/visual feedback and rewards to indicate if the trial was performed correctly or incorrectly. After each assigned session, the difficulty of the next session is updated to ensure that each participant is appropriately challenged.

DEVICE

BrainHQ Computerized Cognitive Training - Visual Cognitive Control Training Paradigm

The Cognitive Training is a program consisting of the follow set of exercises developed by Posit Science Corporation (BrainHQ) which is to be evaluated for Visual Cognitive Control Training: Mind Bender; Divided Attention; Card Shark; and Freeze Frame. Participants use a standard web browser on a broadband connected computer and go to the study web site. Participants perform multiple trials over the course of a session, with auditory/visual feedback and rewards to indicate if the trial was performed correctly or incorrectly. After each assigned session, the difficulty of the next session is updated to ensure that each participant is appropriately challenged.

Sponsors & Collaborators

• National Institute of Mental Health (NIMH)

  collaborator NIH

• University of Minnesota

  lead OTHER

Principal Investigators

• Caroline Demro, PhD · University of Minnesota Department of Psychiatry and Behavioral Sciences

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

30 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2022-07-27

Primary Completion

2025-09-30

Completion

2025-09-30

Countries

• United States

Study Locations