MedTrace Logo

Real-time fMRI Neurofeedback in Patients With Schizophrenia and Auditory Hallucinations

NCT05299749 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 104

Last updated 2025-09-18

No results posted yet for this study

Summary

Neurofeedback intervention aimed to regulate the superior temporal gyrus (STG) activation and default mode network (DMN) connectivity as well as to reduce the auditory hallucinations (AH) schizophrenia patients with medication resistant AH.

Conditions

  • Schizophrenia
  • Auditory Hallucination
  • Treatment-resistant Schizophrenia

Interventions

OTHER

stg-rt-fMRI-Neurofeeback

the patients will receive real-time feedback from the brain activity of the superior temporal gyrus

OTHER

sham-rt-fMRI-Neurofeedback

the patients will receive real-time feedback from the brain activity of the somato-motor cortex

Sponsors & Collaborators

  • Mclean Hospital

    collaborator OTHER

  • Northeastern University

    collaborator OTHER

  • Cambridge Health Alliance

    collaborator OTHER

  • Boston VA Research Institute, Inc.

    lead OTHER

Principal Investigators

  • margaret niznikiewicz · Boston VA Research Institute, Inc.

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-03-01
Primary Completion
2026-06-30
Completion
2026-06-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05299749 on ClinicalTrials.gov