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Measuring Time Windows in Patients With Schizophrenia and Healthy Controls

NCT00350805 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 126

Last updated 2017-10-05

No results posted yet for this study

Summary

Abnormalities in the ability to distinguish events in time may have a great impact on everyday life. The main objective of the study is to evaluate the magnitude of the temporal windows in schizophrenia, i.e. the time interval during which two events are perceived as synchronous. The investigators test the hypothesis that these temporal windows are enlarged, and check the relationship between this impairment and disorganization symptoms, in order to explore the link between this cognitive impairment and clinical symptoms. They explore also the neurobiological bases of the impairment by means of electroencephalogram (EEG) recordings. Event-related potentials (N50) will reveal whether or not the coding of the stimuli has the same temporal characteristics in patients and controls. The distribution and amplitude of oscillatory activities will be analyzed as a function of the synchronous or asynchronous response of the subject, thus allowing to explore the links between synchrony perception and neuronal synchronization phenomena.

Conditions

Interventions

PROCEDURE

EEG

One 20 minutes session

Sponsors & Collaborators

  • Institut National de la Santé Et de la Recherche Médicale, France

    collaborator OTHER_GOV

  • Centre National de la Recherche Scientifique, France

    collaborator OTHER

  • Institut de Physique Biologique de Strasbourg

    collaborator UNKNOWN

  • University Hospital, Strasbourg, France

    lead OTHER

Principal Investigators

  • Anne GIERSCH, MD · Institut National de la Santé Et de la Recherche Médicale, France

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2005-09-30
Primary Completion
2012-04-30
Completion
2012-12-31

Countries

  • France

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00350805 on ClinicalTrials.gov