Drug-soaked paper has become the most commonly found drug in Ohio prisons and was tied to at least 13 fatal K2 overdoses in 2024. Convictions in the state’s largest prison drug conspiracy case detailed how the paper was smuggled and sold.
A longitudinal study of 460,000 teenagers found adolescent cannabis use was linked to higher risks of later bipolar, psychotic, anxiety and depression diagnoses. Separate research and expert guidance say THC effects, especially long term, still need more study.
Neurocrine Biosciences initiated and dosed the first patients in a Phase 2 trial of NBI-1117570 in adults with schizophrenia. Nxera Pharma said it will receive US$22.5 million in milestone payments to be recognised as Q1 FY2026 revenue.
Research reveals how ectopic NMDA receptor expression in triple-negative breast cancer triggers autoimmune disease through antibody maturation. The study shows NMDAR expression recruits B cells and drives affinity maturation, producing antibodies that can cross the blood-brain barrier and cause neurological symptoms while constraining tumor growth.
A longitudinal study of 460,000 teenagers found that adolescent cannabis use increases the risk of developing bipolar and psychotic disorders by twofold, as well as raising risks for depression and anxiety.
A phase IIa clinical trial found that a single intravenous dose of dimethyltryptamine (DMT) with psychological support rapidly reduced depressive symptoms in 34 adults with major depressive disorder, with improvements sustained for up to three months.
Researchers identified shared white matter alterations in the corpus callosum as a common biomarker across schizophrenia and bipolar disorder, supporting the concept of a psychosis spectrum rather than distinct disorders.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07503093 |
Pilot Study of Sensor-Informed Smartphone-based Mental Health Interventions for Mood in Early Psychosis |
NOT_YET_RECRUITING | NA |
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Improving Health Literacy in Patients With Schizophrenia Spectrum Disorder |
NOT_YET_RECRUITING | NA |
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The Mouth Matters in Mental Health Trial -2 |
NOT_YET_RECRUITING | NA |
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NOT_YET_RECRUITING | NA |
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Acceptability, Feasibility and Preliminary Outcomes of the Kiso Mind App for Outpatients With Schizophrenia Spectrum Disorders |
RECRUITING | NA |
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Strategic Timing of Resistance Training to Guard Against Antipsychotic-Induced Metabolic Syndrome |
NOT_YET_RECRUITING | NA |
| NCT07364825 |
Acute Psychiatric Care at Home for Lower-risk Patients With Acute Psychiatric Illness Who Require Inpatient Care |
ACTIVE_NOT_RECRUITING | NA |
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Assessment and Evolution of Narrative Identity and Its Relationship to Subjective Multidimensional Well-being and Multidimensional Recovery in First Episode Psychosis |
NOT_YET_RECRUITING | |
| NCT07326124 |
Stratification and Treatment in Early Psychosis Study -ASSIST |
NOT_YET_RECRUITING | PHASE3 |
| NCT07263022 |
Cognitive Strategies in Early Psychosis 2 |
NOT_YET_RECRUITING | PHASE3 |
