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Inulin and the Gut Microbiota in Healthy Adults

NCT05399316 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2025-05-02

No results posted yet for this study

Summary

In this study the effects of a fibre dietary supplement on the gut microbiome in healthy adults will be investigated. For this purpose, a 14-day dietary supplementation with inulin or placebo (maltodextrin) will be carried out in healthy adults. The main objective of the study is to investigate inulin-induced changes in gut bacterial composition, bacterial gene expression, bacterial metabolite production and associated immune system changes.

Conditions

  • Gut Microbiota Dysbiosis and Nutrition

Interventions

DIETARY_SUPPLEMENT

Inulin

Natural fiber supplement extracted from chicory

DIETARY_SUPPLEMENT

Maltodextrin

Natural non-fermentable sugar

Sponsors & Collaborators

  • Experimental and Clinical Research Center

    lead OTHER

Principal Investigators

  • Nicola Wilck, MD · Charite University

  • Hendrik Bartolomaeus, MD · Charite University

  • Victoria McParland, PhD · ECRC

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-06-15
Primary Completion
2022-12-31
Completion
2022-12-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05399316 on ClinicalTrials.gov