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Probiotic Supplementation and Exercise Performance in the Heat

NCT05389033 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2023-03-23

No results posted yet for this study

Summary

Endurance athletes will be invited to participate in the following study. Subjects will visit the laboratory on three occasions, each time following an overnight fast. Briefly, following an initial assessment and familiarisation, participants will be required to complete an endurance bout of cycling exercise in hot environmental conditions before and after 4 weeks of supplementing with a probiotic or placebo. During the exercise bouts, breath samples will be collected for measurements of whole-body metabolism, blood samples will be collected to assess serum metabolites and markers of gastrointestinal (GI) damage, and subjective measures of effort and symptoms of GI thermal distress will be collected. Before and after each exercise bout, participants will be required to provide a faecal sample for analysis of the microbiome and GI inflammation

Conditions

  • Acute Exercise
  • Probiotics

Interventions

DIETARY_SUPPLEMENT

Probiotic bacteria

28 days daily supplementation with active probiotic

OTHER

Placebo Capsule

28 days daily supplementation with placebo

Sponsors & Collaborators

  • Liverpool John Moores University

    lead OTHER

Principal Investigators

  • Jamie N Pugh, PhD · Liverpool John Moores University

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-07-15
Primary Completion
2023-04-10
Completion
2023-04-10

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05389033 on ClinicalTrials.gov