Role of miRNAs in CVD and Periodontitis
NCT05383794 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 115
Last updated 2022-05-20
Summary
Several micro-RNA plays a key role in endothelial function and may be a link for the known interaction of periodontitis and cardiovascular disease. The investigators compared the impact of gingival health, periodontitis (CP), cardiovascular disease or of both diseases (CP +cardiovascular disease) on gingival crevicular fluid miRNA 7a-5p, miRNA 21-3p, miRNA 21-5p, miRNA 200b-3p, miRNA 200b-5p, miRNA 100-5p, miRNA 125-5p levels.
Conditions
- Cardiovascular Diseases
- Periodontal Diseases
Interventions
- OTHER
-
Observation of Evaluation of gingival crevicular fluid miRNA 7a-5p, miRNA 21-3p, miRNA 21-5p, miRNA 200b-3p, miRNA 200b-5p, miRNA 100-5p, miRNA 125-5p levels.
Evaluation of gingival crevicular fluid miRNA 7a-5p, miRNA 21-3p, miRNA 21-5p, miRNA 200b-3p, miRNA 200b-5p, miRNA 100-5p, miRNA 125-5p levels.
Sponsors & Collaborators
-
University of Catania
lead OTHER
Principal Investigators
-
Gaetano Isola · Università degli Studi di Catania
Eligibility
- Sex
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-04-01
- Primary Completion
- 2021-10-30
- Completion
- 2021-12-15
Countries
- Italy
Study Locations
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