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Efficacy Long-term Dietary Nitrate Consumption to Plasma Nitrite Conversion

NCT05380167 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 13

Last updated 2022-05-25

No results posted yet for this study

Summary

The objective of this study was to determine the chronic effects of beetroot juice supplementation on the acute (90-minute post nitrate consumption) efficacy of converting dietary nitrate to plasma nitrate and plasma nitrite in healthy middle-to-older aged adults. the investigators were also interested in determining the effect of this intervention on fasting levels of plasma nitrate and nitrite over time. Furthermore, the number of participants classified as "non-responders" was determined based on increases in plasma nitrite achieved using tolerable volumes of beetroot juice by other studies.

Conditions

  • Cardiovascular Diseases in Old Age

Interventions

DIETARY_SUPPLEMENT

BRJ Nitrate

Participants in this group drank daily for 12 weeks a 70 mL bottle of Beet It Sport drink with nitrate.

DIETARY_SUPPLEMENT

BRJ Placebo

Participants in this group drank daily for 12 weeks a 70 mL bottle of Beet It Sport drink without nitrate

Sponsors & Collaborators

  • Wake Forest University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-09-01
Primary Completion
2019-05-01
Completion
2019-05-01

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05380167 on ClinicalTrials.gov