Effects of Dietary Nitrate From Vegetable/Fruit Juice on Cerebral Blood Flow Parameters
NCT01169662 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2010-10-13
Summary
Nitrate provides the body with an alternative source of Nitric Oxide which plays a large role in promoting blood flow and reducing blood pressure. Nitrate supplementation with vegetable/fruit juice has recently been shown to reduce blood pressure and reduce energy expenditure during low intensity exercise. Such findings combined with the previously known biological effects of nitric oxide would suggest that nitrate supplementation would also impact on blood flow. The aim of this study is to examine the effects of dietary nitrate supplementation via vegetable/fruit juice drink on cerebral (brain) blood flow (using Near Infrared Spectroscopy).
Conditions
- Cerebrovascular Circulation
- Cognitive Impairment
Interventions
- DIETARY_SUPPLEMENT
-
Vegetable/fruit juice
450ml active juice, 45ml no added sugar fruit squash (for flavour)
- DIETARY_SUPPLEMENT
-
Placebo juice
50 ml No Added Sugar fruit squash, 45 ml Pressed Apple Juice, 405ml with water.
Sponsors & Collaborators
-
Northumbria University
lead OTHER
Principal Investigators
-
David Kennedy · Northumbria University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- TRIPLE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 35 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2010-02-28
- Primary Completion
- 2010-07-31
- Completion
- 2010-07-31
Countries
- United Kingdom
Study Locations
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