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Clinical Registry of Long-Term Dental Outcomes in Head and Neck Cancer Patients

NCT05325970 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 350

Last updated 2026-02-06

No results posted yet for this study

Summary

The current study (ORARAD II) will examine participants of the original cohort for a visit roughly 7 years after the start of RT. The primary outcomes will be the 7-year rate of dental caries, periodontal disease, tooth loss, osteoradionecrosis and salivary flow.

Conditions

Sponsors & Collaborators

  • National Institute of Dental and Craniofacial Research (NIDCR)

    collaborator NIH

  • University of Minnesota

    collaborator OTHER

  • UConn Health

    collaborator OTHER

  • University of Pennsylvania

    collaborator OTHER

  • Brigham and Women's Hospital

    collaborator OTHER

  • NYU Langone Health

    collaborator OTHER

  • University of North Carolina

    collaborator OTHER

  • Wake Forest University Health Sciences

    lead OTHER

Principal Investigators

  • Michael T. Brennan, DDS, MHS · Wake Forest University Health Sciences

  • Rajesh V. Lalla, DDS, PhD · UConn Health

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-02-28
Primary Completion
2026-06-30
Completion
2026-06-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05325970 on ClinicalTrials.gov