Role of Immune Activation in Response of Head and Neck Squamous Cell Carcinoma to Therapy
NCT01358097 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 33
Last updated 2014-04-10
Summary
The purpose of this study is to investigate the role of the immune system in the response of squamous cell cancers of the head and neck to treatment that includes radiation therapy. Current research demonstrates that several natural immune cells and molecules affect the way the body's immune system interacts with a cancerous growth. Some cancers may be related to infection with a virus, such as the Human Papilloma Virus (HPV). Studying the activity of the immune system in head and neck cancers, especially cancers related to HPV infections, can provide valuable information to better understand the body's interaction with cancer cells.
Conditions
- Head and Neck Cancer
- Oropharyngeal Cancer
- Human Papillomavirus
- Squamous Cell Cancer
Sponsors & Collaborators
-
Icahn School of Medicine at Mount Sinai
lead OTHER
Principal Investigators
-
Andrew Sikora, MD, PhD · Icahn School of Medicine at Mount Sinai
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2010-10-31
- Primary Completion
- 2013-09-30
- Completion
- 2013-09-30
Countries
- United States
Study Locations
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