Phase II Trial Evaluating Elimination of Radiation Therapy
NCT00593840 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 74
Last updated 2026-05-19
Summary
The purpose of this study is to determine if reducing or eliminating radiation treatment to one or both sides of the neck where there is no evidence of cancer can help spare the side effects of radiation treatment for head and neck cancer. In this study, the investigators plan to reduce the amount of radiation treatment received to healthy tissue
Conditions
- Cancer of the Larynx
Interventions
- RADIATION
-
Intensity modulated radiation therapy
Sponsors & Collaborators
-
Washington University School of Medicine
lead OTHER
Principal Investigators
-
Wade Thorstad, MD · Washington University School of Medicine
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-04-11
- Primary Completion
- 2014-02-28
- Completion
- 2027-04-30
Countries
- United States
Study Locations
More Related Trials
-
Combination Chemotherapy Plus Radiation Therapy To Preserve the Larynx in Patients With Cancer of the Hypopharynx or Larynx
NCT00002839 ·Status: COMPLETED ·Phase: PHASE3
-
A Phase I/II Study of the Use of Intensity Modulated Radiotherapy (IMRT) in Cancer of the Thyroid, Larynx and Hypopharynx
NCT02055989 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Cisplatin and Radiation Therapy in Treating Patients With Stage IV Cancer of the Head and Neck
NCT00002932 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer
NCT00352118 ·Status: TERMINATED ·Phase: PHASE2
-
High-Dose Radiation Therapy Plus Chemotherapy in Treating Patients With Advanced Nose or Throat Cancer
NCT00052429 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Neoadjuvant Immunoradiotherapy in Head & Neck Cancer (NIRT 2-HNC)
NCT04938609 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Involved Field Elective Volume De-Intensification Radiation Therapy for Head and Neck Cancer
NCT03067610 ·Status: COMPLETED ·Phase: PHASE2
-
Phase II Study Exploring Five Fractions of Post-operative Radiation Therapy in Head and Neck Cancer
NCT05648461 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
S0216, Combination Chemotherapy and RT in Treating Patients With Stage III or Stage IV Head and Neck Cancer
NCT00054054 ·Status: COMPLETED ·Phase: PHASE2
-
Induction TPN Followed by Nivolumab With Radiation in Locoregionally Advanced Laryngeal and Hypopharyngeal Cancer
NCT03894891 ·Status: COMPLETED ·Phase: PHASE2
-
Gefitinib and Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III or Stage IV Head and Neck Cancer
NCT00033449 ·Status: TERMINATED ·Phase: PHASE1
-
Radiation Therapy and Docetaxel in Treating Patients With HPV-Related Oropharyngeal Cancer
NCT01932697 ·Status: COMPLETED ·Phase: PHASE2
-
Docetaxel and Radiation Therapy in Treating Patients With Stage II or Stage III Cancer of the Larynx or Hypopharynx
NCT00243113 ·Status: COMPLETED ·Phase: PHASE2
-
Docetaxel and S-1 Followed By Radiation Therapy and Low-Dose Cisplatin in Treating Patients With Stage III or Stage IV Head and Neck Cancer
NCT00625937 ·Status: UNKNOWN ·Phase: PHASE2
-
Chemotherapy Plus Radiation Therapy in Treating Patients With Previously Untreated Thyroid Cancer
NCT00004089 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy Plus Radiation Therapy in Treating Patients With Head and Neck Cancer
NCT00002951 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy and Radiation Therapy With or Without Lapatinib in Treating Patients With Locally Advanced Cancer of the Larynx or Hypopharynx
NCT00498953 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer
NCT03952585 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2/PHASE3
-
Radiation Therapy With or Without Chemotherapy in Treating Patients With Head and Neck Cancer That Has Been Removed During Surgery
NCT00002670 ·Status: COMPLETED ·Phase: PHASE3
-
Radiotherapy in Combination With Atezolizumab Prior to Surgical Resection for HPV Unrelated HNSCC
NCT05053737 ·Status: COMPLETED ·Phase: PHASE1
-
Trial of Laryngeal Preservation Comparing Induced CT Followed by RT vs CT Concomitant to RT
NCT03340896 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
S9709, Laser Surgery Plus Radiation Therapy in Treating Patients With Early Stage Cancer of the Larynx
NCT00003040 ·Status: TERMINATED ·Phase: PHASE2
-
Stereotactic Radiosurgery in Treating Patients With Locally Advanced or Recurrent Head and Neck Cancer
NCT00851253 ·Status: COMPLETED ·Phase: NA
-
Lymphoscintigraphy Directed Elective Neck Radiation for p16+ Favorable Risk Oropharynx Cancer
NCT05800574 ·Status: RECRUITING ·Phase: PHASE2
-
Web-Based Program in Helping Patients With Head and Neck Cancer Adhere to Swallowing Exercises and Coping Strategies
NCT04003051 ·Status: RECRUITING ·Phase: PHASE2