Interventions in Mathematics and Cognitive Skills

Summary

The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including those with mathematical learning disabilities (MLD).

Conditions

• Math Learning Disability
• Child Development
• Developmental Disability
• Learning Disabilities
• Learning Disabled
• Learning Curve
• Mathematics Disorder
• Dyscalculia
• Dyscalculia, Primary
• Dyscalculia, Acquired
• Specific Learning Disorder, With Impairment in Mathematics
• Individuality
• Behavior, Child
• Behavior and Behavior Mechanisms
• Behavior
• Decision Making
• Neuronal Plasticity
• Cognition
• Cognition Disorder
• Cognitive Dysfunction
• Cognitive Change
• Cognitive Impairment, Mild
• Cognitive Developmental Delay
• Cognitive Orientation
• Cognitive Delay, Mild
• Cognitive Deficits, Mild
• Cognitive Abnormality
• Neuroscience

Interventions

OTHER

Interventions in Mathematics and Cognitive Skills - Experimental

After study participants have completed screenings to meet our inclusion criteria, participants will take part in the pre-training MRI brain scan (if eligible) and behavioral assessments and will then be assigned to the intervention for 6 weeks. During this training, participants will spend three days each week completing a set of problems at their home on a tablet that we provide them. Participants will receive one-to-one training with a member of our research team once a week. Following the completion of the 6-week training program, participants will be asked to complete a second MRI brain imaging session (for those who completed pre-training MRI) and post-measure appointments in order to assess immediate effects of the training program. Participants will also be invited to return for follow-up testing after six months in order to assess the long- lasting effects of the training program.

OTHER

Interventions in Mathematics and Cognitive Skills - Active Comparator

After study participants have completed screenings to meet our inclusion criteria, participants will take part in the pre-training MRI brain scan (if eligible) and behavioral assessments and will then be assigned to the intervention for 6 weeks. During this training, participants will spend three days each week completing a set of problems at their home on a tablet that we provide them. Participants will receive one-to-one training with a member of our research team once a week. Following the completion of the 6-week training program, participants will be asked to complete a second MRI brain imaging session (for those who completed pre-training MRI) and post-measure appointments in order to assess immediate effects of the training program. Participants will also be invited to return for follow-up testing after six months in order to assess the long- lasting effects of the training program.

Sponsors & Collaborators

• Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

  collaborator NIH

• Stanford University

  lead OTHER

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

6 Years

Max Age

12 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2023-05-05

Primary Completion

2026-06-30

Completion

2026-06-30

Countries

• United States

Study Locations