Understanding the Risk of Blood Clots and Bleeding in Patients With Hematological Malignancies, HAT Study
NCT05053100 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2025-05-02
Summary
This study evaluates the risks and experience of blood clots and bleeding in patients with blood cancers. While it is standard of care to use medications to reduce the risk of blood clots in hospitalized individuals, some patients with blood cancers have low platelet counts that can increase the concern for bleeding complications associated with these medications. At this time, the optimal management strategies for blood clots are not well known for patients with blood cancers. This pilot study evaluates additional information that could help doctors know which patients are at highest risk for blood clots.
Conditions
- Acute Leukemia
- Deep Vein Thrombosis
- Hematopoietic and Lymphoid Cell Neoplasm
- Hodgkin Lymphoma
- Myeloproliferative Neoplasm
- Non-Hodgkin Lymphoma
- Plasma Cell Myeloma
- Thrombocytopenia
Interventions
- PROCEDURE
-
Biospecimen Collection
Undergo collection of blood
- OTHER
-
Electronic Health Record Review
Undergo electronic health record review
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Leslie J. Padrnos, MD · Mayo Clinic
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-08-17
- Primary Completion
- 2024-07-05
- Completion
- 2024-07-05
Countries
- United States
Study Locations
More Related Trials
-
Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome
NCT02269592 ·Status: RECRUITING
-
Clinical, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Hematologic Cancer
NCT00039676 ·Status: ACTIVE_NOT_RECRUITING
-
Selecting a Favorable KIR Donor in Unrelated HCT for AML
NCT01288222 ·Status: COMPLETED ·Phase: NA
-
Familial Investigations of Childhood Cancer Predisposition
NCT03050268 ·Status: RECRUITING
-
Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family Members
NCT00071045 ·Status: RECRUITING
-
Cardiotoxic Effects of Chemotherapy in Patients With Sarcomas: A Two and Three-dimensional Echocardiographic Speckle Tracking Imaging Study
NCT06511388 ·Status: TERMINATED
-
Thrombin Generation and Prediction of Thromboembolic Events in Oncology Patients at Risk
NCT06051214 ·Status: RECRUITING ·Phase: NA
-
Biology and Genetics of Smouldering Myeloma
NCT05047107 ·Status: UNKNOWN
-
LCI-HEM-SPEC-001: Tissue Collection for Genetic Analysis of Acute Myelogenous Leukemia
NCT01999556 ·Status: COMPLETED
-
Biomarkers Related to Thrombosis in Patients With Newly Diagnosed Multiple Myeloma Receiving Chemotherapy
NCT01132833 ·Status: COMPLETED
-
Evaluation of Fibrin Structure Marker in Cancer Patients Treated and Not Treated With LMWH
NCT02552381 ·Status: COMPLETED
-
Collection Of Tissue, Blood, and Other Specimens From Patients With Head and Neck Tumors To Study the Causes, Diagnosis, Prevention and Treatment of Cancers
NCT00580203 ·Status: COMPLETED
-
Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
NCT01137643 ·Status: RECRUITING
-
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
NCT05334069 ·Status: RECRUITING
-
Characteristics and Outcomes of Patients With Hematological Malignancies
NCT06402175 ·Status: NOT_YET_RECRUITING
-
Pre-malignant States to Hematologic Malignancies in Firefighters
NCT06870760 ·Status: RECRUITING
-
Development of a Risk Stratification Score for Recurrent Venous Thromboembolism and Treatment-related Clinically Relevant Bleeding in Patients With Cancer-associated Thrombosis
NCT06894576 ·Status: RECRUITING
-
Measurable Residual Disease Detection Using Tumor-Informed ctDNA Surveillance After Curative-Intent Treatment in HPV-Independent Squamous Cell Carcinoma of the Head and Neck
NCT06744296 ·Status: RECRUITING
-
Examining Blood and Tissue Samples to Identify Diagnostic Markers in Patients With Metastatic Cancer Undergoing Tumor Removal
NCT05530759 ·Status: RECRUITING
-
Collection of Tumor Tissue, Blood and Spinal Fluid From Patients With Brain or Spine Tumors
NCT00580463 ·Status: COMPLETED
-
Pre-myeloid Cancer and Bone Marrow Failure Clinic Study
NCT02958462 ·Status: RECRUITING ·Phase: NA
-
Prospective and Retrospective Cohort Study to Find New Prognostic Factors and Therapeutic Targets in Patients With Newly Diagnosed or Relapsed Malignant Hematologic Disorder Excluding Acute Leukemia
NCT02330718 ·Status: UNKNOWN
-
Cytogenetic Analysis of Bone Marrow Specimen Prior to High Dose Chemotherapy and Autologous Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma or Hodgkin's Disease
NCT00534820 ·Status: COMPLETED ·Phase: NA
-
Pro-Active Genetic Testing in Patients With Solid Tumors, Inherit Study
NCT04456140 ·Status: COMPLETED ·Phase: PHASE1
-
Detection of IDH2 Mutations and Monitoring Molecular Residual Disease in Patients With AML
NCT03537560 ·Status: COMPLETED