Pathogenesis of Hematologic Malignancies
NCT01728402 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 5000
Last updated 2026-02-17
Summary
The cause of blood and bone marrow cancers is poorly understood; however, most research focuses on how cancer cells grow and develop. Because the causes of these cancers are unknown, current treatments may be unnecessarily harsh and often do not provide a cure. Identifying the causes of blood cancers would allow for the development of treatments that are more likely to provide a cure. To find the causes of blood and bone marrow cancers, we will look for specific cancer cell abnormalities that are responsible for cancer cell growth. We will then look to see if drugs that can reverse these abnormalities can kill cancer cells.
Conditions
- Acute Leukemia
- Lymphoproliferative Disorders
- Myeloproliferative Disorders
- Myelodysplastic Syndromes
Interventions
- PROCEDURE
-
blood draw, bone marrow procedure, or tissue biopsy
Sponsors & Collaborators
-
National Institutes of Health (NIH)
collaborator NIH -
National Cancer Institute (NCI)
collaborator NIH -
OHSU Knight Cancer Institute
lead OTHER
Principal Investigators
-
Cristina Tognon, PhD · OHSU Knight Cancer Institute
Eligibility
- Min Age
- 1 Year
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-09-30
Countries
- United States
Study Locations
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