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Organ-substituting Technologies in the Treatment of Heart and Pulmonary Failure

NCT05042622 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2021-09-13

No results posted yet for this study

Summary

The implementation of this project will improve the effectiveness of surgical treatment and reduce the level of complications and mortality among patients with heart failure and heart failure in the terminal stage.

The goal of the study. Improvement of organ-substituting technologies in the treatment of heart and respiratory failure.

Objectives of the study. Objective 1. To study the restoration of organ function during implantation of extracorporeal membrane oxygenation (ECMO), as an organ replacement, in cardiac and / or respiratory failure.

Objective 2. To study the results of applying organ-substituting technologies in the treatment of sepsis.

Conditions

  • Acute Respiratory Distress Syndrome
  • Septic Shock
  • Sepsis

Interventions

DEVICE

Cytokine adsorber filter

• Intervention group #1 a cytokine adsorber will be used (30 patients): patients on ECMO - subgroup A; septic patients - subgroup B.

DEVICE

Extracorporeal hemoperfusion cartridge

• Intervention group #2 an extracorporeal hemoperfusion cartridge will be used (30 patients): patients on ECMO - subgroup C, septic patients - subgroup D.

Sponsors & Collaborators

  • Ministry of Education and Science, Republic of Kazakhstan

    collaborator OTHER_GOV

  • National Research Center for Cardiac Surgery, Kazakhstan

    lead OTHER

Principal Investigators

  • Timur Lesbekov, PhD, MD · National research Center for Cardiac Surgery JSC

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-01-01
Primary Completion
2023-12-31
Completion
2023-12-31

Countries

  • Kazakhstan

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05042622 on ClinicalTrials.gov