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Cardiopulmonary Bypass and Ventricular Remodeling

NCT06256965 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 12

Last updated 2024-02-13

No results posted yet for this study

Summary

The goal of this observational study is determine if reduced ventricular ejection fraction is a factor that determines a pro-oxidant imbalance in patients subjected to cardiac surgery with cardiopulmonary bypass.

The main questions are:

* 1\. Preoperative reduced left ventricular function determines higher blood and atrial tissue oxidative stress in patients subjected to cardiopulmonary bypass
* 2\. Oxidative stress markers in atrial tissue of cardiac surgical patients with develop atrial fibrillation The main tasks participants will be asked to do is register the symptoms of arrhythmia and heart failure. Also, obtain a electrocardiographic register if any present palpitations or chest pain with clinical significance This study not present a comparison group.

Conditions

Interventions

DIAGNOSTIC_TEST

Detection of peri-operative atrial fibrillation

atrial tissue and plasma from patients with atrial fibrillation detection were analyzed for determine lipid and protein oxidation, and detect markers of myocardial injury.

Sponsors & Collaborators

  • Hospital del Salvador

    collaborator OTHER

  • University of Chile

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-10-04
Primary Completion
2021-11-15
Completion
2022-06-13

Countries

  • Chile

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06256965 on ClinicalTrials.gov