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Specific miRNAs in Sepsis and Nephrotoxic Antibiotic Treatment

NCT04991376 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 53

Last updated 2022-12-06

No results posted yet for this study

Summary

Critically ill patients are prone to develop acute kidney injury due to sepsis itself and by administration of potentially nephrotoxic antibiotic treatment (vancomycin or gentamicin). Blood-specific miRNA levels associated with renal tubular damage change in patients treated with vancomycin or gentamicin compared to septic patients treated with other antimicrobials.

Conditions

Interventions

DIAGNOSTIC_TEST

Blood-specific miRNA levels

Blood-specific miRNA levels associated with renal tubular damage change in patients treated with vancomycin or gentamicin compared to septic patients treated with other antimicrobials.

Sponsors & Collaborators

  • Palacky University

    collaborator OTHER

  • University Hospital Olomouc

    collaborator OTHER

  • University of Ostrava

    collaborator OTHER

  • Technical University of Ostrava

    collaborator UNKNOWN

  • University Hospital Ostrava

    lead OTHER

Principal Investigators

  • Naděžda Petejová, Assoc.Prof.,MD,PhD,MSc · University Hospital Ostrava

Eligibility

Min Age
18 Years
Max Age
95 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-05-02
Primary Completion
2021-06-30
Completion
2022-12-01

Countries

  • Czechia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04991376 on ClinicalTrials.gov