Midkine and ACE-Ang II Induced Endothelial Injury in Sepsis
NCT02605681 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 26
Last updated 2018-12-12
Summary
Plasma midkine has reported to be elevated in infection and a regulator of angiotensin-converting enzyme (ACE). We aimed to investigate the plasma midkine in septic patients and its association with 28-day mortality and organ function, and also with plasma ACE and angiotensin II.
Conditions
Sponsors & Collaborators
-
Southeast University, China
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-11-01
- Primary Completion
- 2018-03-31
- Completion
- 2018-06-15
Countries
- China
Study Locations
More Related Trials
-
Study on the Construction and Application of Early Warning Model of Sepsis in Critically Ill Patients
NCT06904001 ·Status: ENROLLING_BY_INVITATION
-
The Effect of rTEM in the Prognosis and Severity of Sepsis Induced ARDS
NCT06063707 ·Status: NOT_YET_RECRUITING
-
Validation of Molecular and Protein Biomarkers in Sepsis
NCT04289506 ·Status: UNKNOWN
-
Defining Circulating Micro-RNA Biomarkers for the Early Diagnosis and Prognosis of Sepsis
NCT02544490 ·Status: COMPLETED
-
The Predictive Value of Hepatocyte Growth Factor and Soluble Receptor s-Met in Sepsis
NCT03340649 ·Status: UNKNOWN
-
Relation Between Mean Arterial Pressure and Renal Resistive Index in the Early Phase of Septic Shock
NCT04281277 ·Status: COMPLETED ·Phase: NA
-
Molecular Subtype-Specific Mechanisms and Therapeutic Strategies in Sepsis
NCT06287684 ·Status: RECRUITING
-
Construction of a Database for the Life-cycle Sepsis-specific Disease Cohort
NCT04872010 ·Status: UNKNOWN
-
TRIM25 in Septic Patients
NCT07320638 ·Status: ENROLLING_BY_INVITATION
-
Amino Acids Expression Profiling of Patients With Sepsis
NCT01818830 ·Status: UNKNOWN
-
Change in MAPSE During Treatment of Sepsis
NCT05634733 ·Status: RECRUITING
-
MiRNAs Evaluating Lymphocyte Proliferation and Apoptosis as Well as Prognosis of Sepsis
NCT02756559 ·Status: UNKNOWN
-
The Effect of Increasing the Mean Arterial Pressure on the Microcirculation and the Prognosis of Patients With Septic Shock
NCT04136080 ·Status: UNKNOWN ·Phase: NA
-
The Role of NLR in the Diagnosis and Prognosis of Sepsis
NCT05636202 ·Status: COMPLETED
-
A Blood Test to Diagnose Sepsis in Symptomatic Adults and Children
NCT05142813 ·Status: UNKNOWN
-
Angiotensin in Septic Kidney Injury Trial
NCT00711789 ·Status: UNKNOWN ·Phase: PHASE2
-
We Collected Blood Samples From Septic Shock Patients and Measured ELABELA, Creatinine, and NGAL Levels. Survival After 7 Days Was Recorded and Analyzed to Evaluate the Potential of Serum ELABELA as an Early Diagnostic Marker for Sepsis-associated Acute Kidney Injury.
NCT06001294 ·Status: UNKNOWN
-
Effect of R-spondin3 on Sepsis Induced Endothelial Dysfunction
NCT04546919 ·Status: UNKNOWN
-
Albumin Infusion Targets on Mortality in Patients With Abdominal Sepsis
NCT06874634 ·Status: COMPLETED
-
Effect of Albumin Administration on Vasopressor Duration in Resolving Septic Shock
NCT02716597 ·Status: TERMINATED ·Phase: PHASE1
-
Role of the Kallikrein-kinin System in Septic Cardiomyopathy
NCT06080282 ·Status: COMPLETED
-
The Application of SERS and Metabolomics in Sepsis
NCT02213237 ·Status: UNKNOWN
-
The Early Coagulopathy for the Prognosis in Sepsis
NCT04582188 ·Status: UNKNOWN
-
Early Prediction of Sepsis by Using Metabolomics
NCT03996759 ·Status: UNKNOWN
-
Zinc and Inflammation in Sepsis
NCT01328509 ·Status: COMPLETED