Macro and Micro Haemodynamic Responses to Shock in the Renal and Systemic - MICROSHOCK - RENAL
NCT03713307 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 50
Last updated 2018-12-10
Summary
An observational study of the state of the renal and systemic circulations in patients with early septic shock. Both macro and microvascular parameters will be assessed using echocardiography, sublingual incident dark field video-microscopy and renal contrast enhanced ultrasound. Patients will be categorised by KDIGO degree of kidney injury at Day 7 and stratified. Haemodynamic and perfusion based variables over time for these groups will be compared to assess the impact of changes in same on the development of AKI. Lab based work to quantify renal injury biomarkers will also be undertaken.
Conditions
- Acute Kidney Injury
- Septic Shock
Sponsors & Collaborators
-
Royal Centre for Defence Medicine
collaborator OTHER_GOV - lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-11-27
- Primary Completion
- 2020-06-30
- Completion
- 2020-11-30
Countries
- United Kingdom
Study Locations
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