Effect of a Probiotic Strain Lactobacillus Paracasei K56 on Metabolic Symptom - a Pilot Study
NCT04980599 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 118
Last updated 2023-01-10
Summary
Recent data suggest that gut microbiota can function as an environmental factor that modulates the amount of body fat and obese individuals have an altered gut microbiota.The results of previous animal studies have suggest that a probiotic strain Lactobacillus paracasei K56 have reduced high-fat diet induced obesity.
In this before-after pilot study, the participants were randomly assigned to 8 groups to compare the fat-reducing effect of the Lactobacillus paracasei K56 by continuously supplementing different product prototypes , and screen the best probiotic K56 prototype with the effect of fat reduction.
Conditions
- Obesity
- Adiposity
Interventions
- DIETARY_SUPPLEMENT
-
probiotic drink with Lactobacillus paracasei K56
Probiotic drink (K56 10\^11CFU) 350ml/d for 60days
- DIETARY_SUPPLEMENT
-
maltodextrin
maltodextrin ,for 60days
- DIETARY_SUPPLEMENT
-
Probiotic powder E3
Probiotic powder 3.0g/d (K56 10\^10cfu) 60days;
- DIETARY_SUPPLEMENT
-
Probiotic powder E5
probiotic powder 8g/day for 60days
- DIETARY_SUPPLEMENT
-
probiotic capsule E7
probiotic k56 capsule, 2capsules/d (10\^7cfu) for 60days
- DIETARY_SUPPLEMENT
-
probiotic capsule E9
probiotic k56 capsule, 2capsules/d (10\^9cfu) for 60days
- DIETARY_SUPPLEMENT
-
probiotic capsule E10
probiotic k56 capsule, 2capsules/d (10\^10cfu) for 60days
- DIETARY_SUPPLEMENT
-
probiotic capsule E11
probiotic k56 capsule, 4capsules/d (10\^11cfu) for 60days
Sponsors & Collaborators
-
Inner Mongolia Yili Industrial Group Co., Ltd
collaborator INDUSTRY -
Fudan University
lead OTHER
Principal Investigators
-
Ying Feng, Ph.D · Hua Dong Hospita Affiliated to Fu Dan University, Shanghai,China
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2021-01-10
- Primary Completion
- 2021-08-30
- Completion
- 2021-12-31
Countries
- China
Study Locations
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