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Periodontitis in Young Individuals, Follow up of Treatment and Disease Progression Over 10 Years

NCT04926519 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 471

Last updated 2025-09-29

No results posted yet for this study

Summary

The general aim of this project is to get a better understanding how periodontitis develop in young individuals over time and identify factors that contribute to disease recurrence. The investigators also want to see if Stage and Grade of the periodontal disease has a significant impact on disease progression. In addition, another purpose is to identify factors explaining why certain young patients with periodontitis interrupt the periodontal treatment.

The specific aims of the project are:

* To study the periodontal status and the degree of disease progression over 10 years for young individuals with periodontitis at age \< 36 yrs at baseline (study 1)
* To identify factors with a significant influence on periodontitis progression for young individuals with periodontitis at baseline (study 2)
* To identify explanatory factors to discontinuation of periodontal treatment (study 3)
* To identify bio marker and microbiological profiles in young individuals in relation to stage and grade of periodontitis (study 4)

Significance:

A high patient compliance rate and effective supportive treatment to prevent periodontitis progression are crucial conditions for the long-term prognosis. The identification of factors influencing the compliance rate can improve the frequency of individuals following a supportive care program. In addition, long-time follow-up studies of individuals with the diagnosis severe periodontitis at young age are lacking as well as deeper knowledge concerning risk predictors for further disease progression.

The identification of biomarkers or microorganisms that can differentiate between different stage and grade of periodontitis could make it possible to identify individuals with a high risk for disease progression at an early stage.

Conditions

  • Periodontitis

Interventions

OTHER

Type of periodontal treatment

Identify factors that contribute to disease recurrence due to periodontal classification and periodontal treatment. One group have got the diagnosis aggressive periodontitis at baseline and the other group chronic periodontitis. Since 2018 we have the classification system with stage and grade.

Sponsors & Collaborators

Principal Investigators

  • Leif Jansson, DDSPhDAssPro · Folktandvården Stockholm

Eligibility

Max Age
35 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-10-01
Primary Completion
2020-03-30
Completion
2020-08-15

Countries

  • Sweden

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04926519 on ClinicalTrials.gov