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Evaluation of Possible Genes in Periodontal Diseases by Genetic Methods

NCT04026828 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2019-07-25

No results posted yet for this study

Summary

Generalized aggressive Periodontitis (GAgP) and chronic periodontitis (CP) are inflammatory diseases. Little is known about molecular changes and signaling cascade of host response. Inflammatory diseases are undercontrol of genetic and enviromental factors. Transcription factors are gene-specific factors that are often considered to act as a link connecting genetic and enviromental factors.

The aim of this study is to investigate the gene regions that are thought to play a role in the pathogenesis of GAgP and CP, and to interpret new and reliable pathognomonic-prognostic markers in the diagnosis and treatment of these diseases with the help of expression and mutation analyzes and polymorphism studies.

Conditions

  • Generalized Aggressive Periodontitis
  • Chronic Periodontitis

Interventions

GENETIC

Periodontitis Group

Periodontitis group consists of both chronic and aggressive periodontitis patients

Sponsors & Collaborators

  • Kocaeli University

    lead OTHER

Principal Investigators

  • ESRA GUZELDEMIR-AKCAKANAT, DDS, PhD · Kocaeli University

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-09-01
Primary Completion
2021-08-31
Completion
2022-07-15

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04026828 on ClinicalTrials.gov