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Pre-emptive Dexamethasone in Hip Arthroplasty

NCT04898920 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 83

Last updated 2023-02-02

No results posted yet for this study

Summary

* Certain studies suggested that preoperative administration of systemic glucocorticoids in patients undergoing hip or knee arthroplasty surgery may improve the postoperative analgesia owing to their anti-inflammatory effect.
* This study will be carried out on 70 adult patients aged 21 to 75 years admitted to orthopedic operating rooms in Tanta university hospitals for hip surgery under spinal anesthesia. Informed written consent will be obtained from each participant.
* Patients will be randomly distributed into two equal groups using the computer-generated software.

* Control Group: (35 patients) Those patients will receive 10 ml of normal saline before surgery.
* Dexamethasone Group: (35 patients) Those patients will receive 16 mg dexamethasone in 10 ml of normal saline before surgery.
* Primary outcome will be postoperative morphine consumption and the secondary outcome will be the postoperative pain score

Conditions

  • Postoperative Pain

Interventions

DRUG

Normal saline

The patients will receive 10 ml of normal saline as a placebo dexamethasone before surgery.

DRUG

Dexamethasone

Those patients will receive 16 mg dexamethasone in 10 ml of normal saline before surgery.

Sponsors & Collaborators

  • Tanta University

    lead OTHER

Principal Investigators

  • Sameh Abdelkhalik, M.D · Tanta University

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-05-23
Primary Completion
2023-01-28
Completion
2023-01-28

Countries

  • Egypt

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04898920 on ClinicalTrials.gov