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Dexketoprofen and Etoricoxib in Patients Undergoing Hip Arthroplasty

NCT02568735 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2016-05-03

No results posted yet for this study

Summary

The main purpose of this study was to determine the plasma and central nervious system pharmacokinetics of dexketoprofen and etoricoxib. The secondary aim was to asses their effect on the concentrations of interleukin 6, prostaglandin E2 and other proinflammatory markers both in plasma and cerebrospinal fluid. Thirdly, the investigators aimed to evaluate their efficacy in postoperative pain treatment.

Conditions

  • Pain, Postoperative

Interventions

DRUG

Dexketoprofen

After total hip replacement surgery patient were given either etoricoxib or dexketoprofen

DRUG

Etoricoxib

After total hip replacement surgery patient were given either etoricoxib or dexketoprofen

Sponsors & Collaborators

  • Kuopio University Hospital

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-01-31
Primary Completion
2014-12-31
Completion
2014-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02568735 on ClinicalTrials.gov