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High-Dose Steroid for Knee Arthroplasty Patients Expected to Have Postoperative Pain

NCT03763734 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 88

Last updated 2021-06-30

No results posted yet for this study

Summary

The purpose of the Study is to test a higher dose of steroids(Dexamethasone) given just prior to surgery in the setting of Fast-Track Knee surgery with Arthroplasty in a group of expected High Pain Responders and the effect on postoperative pain and postoperative inflammation.

Conditions

  • Postoperative Pain
  • Postoperative Nausea and Vomiting
  • Knee Osteoarthritis
  • Perioperative/Postoperative Complications
  • Surgery
  • Opioid Use
  • Catastrophizing Pain
  • Chronic Pain

Interventions

DRUG

Dexamethasone

An intravenous bolus dose of dexamethasone given prior to surgery.

Sponsors & Collaborators

  • Sygehus Lillebaelt

    collaborator OTHER

  • Copenhagen University Hospital, Hvidovre

    lead OTHER

Principal Investigators

  • Nicolai Bang Foss, Dr.med. · Dept. of Anaesthesia, Hvidovre Hospital, Capital Region of Denmark.

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-01-29
Primary Completion
2021-01-01
Completion
2021-01-01

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03763734 on ClinicalTrials.gov