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Oral and Olfactory Complications of Recovered COVID-19 Patients

NCT04791436 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 402

Last updated 2024-05-13

No results posted yet for this study

Summary

This cohort study aims to investigate the long-standing chemosensory disorders and oral manifestation after recovery of the COVID-19 illness. A correlation between the long-standing symptoms and the COVID-19 severity grade will be very important to understand and clarify the aetiology of these symptoms.

Conditions

  • Oral Complication
  • Dysgeusia
  • Olfactory Disorder

Interventions

DIAGNOSTIC_TEST

Gustatory and olfactory function test

The gustatory and olfactory function will be tested by using the combined Burghart Screening 12 test containing smelling sticks and taste strips (Fa. MediSense, Groningen, Netherlands). Evaluation of taste and smell is performed by offering the sticks/strips and demand a forced multiple choice.

DIAGNOSTIC_TEST

Molecular assessment of saliva

Saliva samples will be taken for molecular biological determination of the oral microbiome. The microbiome is determined at the Institute for Medical Microbiology by 16s-rRNA gene analysis with Next Generation Sequencing and bioinformatics.

Sponsors & Collaborators

  • Masaryk University

    collaborator OTHER

  • University of Kiel

    collaborator OTHER

  • University of Giessen

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-05-01
Primary Completion
2025-01-30
Completion
2025-05-28

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04791436 on ClinicalTrials.gov