Sarcopenia Magnetic Resonance Imaging Evaluation (SUSIE)
NCT04869813 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 70
Last updated 2026-02-11
Summary
The goal of the proposed research is to investigate Magnetic Resonance (MR) Fingerprinting and P-MRS (Phosphorus-31 MR Spectroscopy) imaging for characterization of skeletal muscle in heart failure patients with sarcopenia. Heart failure patients with and without sarcopenia will be scanned using MR Fingerprinting and an existing Post-exercise phosphocreatine (PCr) recovery MR imaging protocol to obtain characteristic profiles of quantitative T1, T2, and PCr recovery rate.
Conditions
Sponsors & Collaborators
-
The Cleveland Clinic
lead OTHER
Principal Investigators
-
W. H. Wilson Tang, MD · The Cleveland Clinic
Eligibility
- Min Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-04-09
- Primary Completion
- 2026-06-30
- Completion
- 2026-12-31
Countries
- United States
Study Locations
More Related Trials
-
Mapping Human Muscle Satellite Cell Fate By Real-Time Imaging
NCT02685319 ·Status: COMPLETED ·Phase: NA
-
Multivariate Biomarker Study for Sarcopenia in Heart Failure
NCT06217640 ·Status: ACTIVE_NOT_RECRUITING
-
Body Composition Ultrasound for Patients With Heart Failure
NCT03948776 ·Status: COMPLETED
-
Blood Flow, Muscle Regeneration and Sarcopenia
NCT01035060 ·Status: COMPLETED
-
Muscle Assessment Through Ultrasound in the Evaluation of Acute Sarcopenia
NCT03740061 ·Status: UNKNOWN
-
Fatigability of Lower Limb Muscle in Older Adults: Protective Effects of Strength Training Exercise in Old Men and Women
NCT03888040 ·Status: RECRUITING ·Phase: NA
-
Changes in Skeletal Muscle Thickness in Patients With Acute Heart Failure
NCT06253104 ·Status: RECRUITING
-
Application of Artificial Intelligence Algorithm Based on CT Imaging for Muscle Parameter Measurement
NCT06845462 ·Status: COMPLETED
-
Imaging Biomarkers of the Effects of a Mixed Exercise Program
NCT03834558 ·Status: COMPLETED ·Phase: NA
-
Muscle Ultrasound for Sarcopenia Leading to Early Detection
NCT02319850 ·Status: COMPLETED
-
Functional Characteristic Properties of Skeletal Muscle Tissue Assessed by P31 Spectroscopy in Young and Older Adults
NCT03336294 ·Status: TERMINATED ·Phase: NA
-
Resistance Exercise for the Prevention of Age-related Sarcopenia
NCT01355861 ·Status: WITHDRAWN ·Phase: NA
-
Role of MicroRNAs on Age and Contraction-induced Skeletal Muscle Growth
NCT02638454 ·Status: COMPLETED ·Phase: NA
-
Multidisciplinary Combined Exercise and Nutrition Intervention for Sarcopenia
NCT04948736 ·Status: COMPLETED ·Phase: NA
-
Effects of Resistance and Endurance Training on Synthesis of Individual Muscle Proteins in Young and Older Adults
NCT01489930 ·Status: COMPLETED ·Phase: NA
-
Muscle Biopsies in Healthy Volunteers
NCT01431677 ·Status: TERMINATED ·Phase: NA
-
Skeletal Muscle Mitochondria in Ageing
NCT06539078 ·Status: RECRUITING
-
SARCOPEDIA - Sarcopenia Diagnostics in Aging Medicine
NCT05263596 ·Status: RECRUITING ·Phase: NA
-
Detection and Treatment of Sarcopenia and Myosteatosis in Older African Americans
NCT02350465 ·Status: UNKNOWN ·Phase: NA
-
Inspiratory Muscle Training Effectiveness in Sympathetic Activity and Functional Capacity in Patients With Heart Failure
NCT02600000 ·Status: UNKNOWN ·Phase: NA
-
Interest of a Tongue Strength Measurement in the Screening for Sarcopenia in Hospitalized Elderly Patients
NCT03417609 ·Status: COMPLETED
-
SCM Muscle as a Marker for Frailty in Patients Undergoing ENT Surgery
NCT06704256 ·Status: RECRUITING
-
Magnetic Resonance and Optical Imaging of Dystrophic and Damaged Muscle
NCT02168114 ·Status: COMPLETED ·Phase: NA
-
Muscle OXPHOS and Nutrient Homeostasis
NCT02920671 ·Status: COMPLETED
-
A Study to Evaluate Breathing Muscle Training in Cardiac Rehab
NCT04984473 ·Status: RECRUITING ·Phase: NA